Ginseng in Treatment of Fatigue in Multiple Sclerosis

Isfahan University of Medical Sciences

Status and phase

Completed

Phase 2

Conditions

Fatigue

Treatments

Drug: Placebo

Drug: Ginseng

Study type

Interventional

Funder types

Other

Identifiers

NCT01712373

ASD-1270

Details and patient eligibility

About

The purpose of this study was to evaluate the efficacy and safety of Ginseng in treatment of fatigue and Quality of Life of MS patients.

Full description

Multiple Sclerosis (MS) is one of the most common non-traumatic causes of disability in the world. It is a chronic inflammatory and demyelinating disorder of the Central Nervous System (CNS) which affects individuals in the productive ages and causes a large burden for years to come. Fatigue is a common complaint and one of the least understood symptoms of MS

Enrollment

60 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

definite diagnosis of relapsing-remitting MS (RRMS) by the MacDonald criteria with a baseline of Expanded Disability Status Score (EDSS)of less than 5.0

Exclusion criteria

prior use of ginseng or any other tonic agents, glucocorticoids, warfarin, digoxin, aspirin, furosemide, caffeine, ephedra and anti-platelet agents within one month prior to enrollment;
Pregnancy or lactation;
history of renal failure; and,
lack of appropriate adherence to the study protocol.