Ginsenoside Improve Metabolic Syndrome

CHA University

Status: Unknown

Conditions: Metabolic Syndrome

Treatments: Dietary Supplement: Dietary fiber fill; Dietary Supplement: Ginsenoside

Study type: Interventional

Funder types: Other

Identifiers

NCT02034136

DH-13722

BD2013-104 (Other Identifier)

Details and patient eligibility

About

Aim : Investigated the effects of Korean red ginseng supplementation on metabolic parameters such as cholesterol, blood pressure and glucose.

Randomized Control Trial.

Full description

Methods : A randomized, double-blind, placebo-controlled, single-center study in 60 subjects who are not taking drugs that could affect metabolic and vascular function. Subjects will be randomized into a Korean red ginseng (3.0g/d) group or placebo group for a 4-week study.

We will collect anthropometric measurements, blood for laboratory testing, inflammatory marker, hormones and mitochondrial DNA copy number.

Subject : Older than 40 years of age, presented with metabolic syndrome. Subjects were excluded if they were taking drugs that could affect metabolic and vascular function, including BP control drug, anti-diabetic drugs and lipid-lowering drugs.

Measurement : We will collect anthropometric measurements and blood for laboratory testing at the initial(week 0) and final (week 4)visits. Serum levels of blood glucose, insulin, total cholesterol, HDL-cholesterol,triglyceride, and DNA copy number of mitochondria.

Enrollment: 60 estimated patients

Sex: All

Ages: 40 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• metabolic syndrome

Exclusion criteria

• Taking drug for lipid-lowering, BP control and anti-diabetic.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Ginsenoside

Experimental group

Description:

Ginsenoside : Intervention : ginsenoside, 3 gram / day, for 28 days in intervention group

Treatment:

Dietary Supplement: Ginsenoside

Dietary fiber fill

Placebo Comparator group

Description:

Dietary fiber fill manufactured to mimic Ginsenoside tablet

Treatment:

Dietary Supplement: Dietary fiber fill