Glasgow Natural History Study Of Covered Coronary Interventions (GNOCCI)

NHS National Waiting Times Centre Board

Status: Completed

Conditions: Coronary Artery Perforation; Coronary Stent Occlusion; Stent Thrombosis

Treatments: Device: Covered coronary stent

Study type: Observational

Funder types: Other

Identifiers

NCT03862352

1.0

Details and patient eligibility

About

Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. The GNOCCI study aims to evaluate long term outcomes after coronary perforation including patients treated with covered stents.

Full description

Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. Using an electronic data base, details of all coronary perforations are identified and anonymised patient and procedural details are recorded.Procedural major adverse cardiac events (pMACE) are defined as a composite of death, myocardial infarction, stroke, target vessel revascularization or cardiac surgery within 24 hours of the index procedure. Two independent cardiologists adjudicate outcomes and differences in opinion are resolved by consensus with a third cardiologist.

The overall GNOCCI study aims are:

1. Evaluate procedural and long term outcomes after coronary perforation
2. Long term safety and clinical events in patients treated with covered stents.

Enrollment: 161 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any coronary artery perforation during percutaneous coronary intervention

Exclusion criteria

• Nil

Trial design

161 participants in 1 patient group

Coronary artery perforation (iatrogenic)

Description:

Any coronary artery perforation defined according to the Ellis criteria.

Treatment:

Device: Covered coronary stent