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GLASS Classification and CLTI

A

Assiut University

Status

Unknown

Conditions

Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Critical limb threatening ischemia "CLTI 'is not a separate local disease but also it is a part of generalized vascular disorder. A clinical syndrome that can be presented by many symptoms and signs as rest pain, gangrene and chronic ulceration more than 2 weeks (1).

Full description

The Global Vascular guidelines 'GVG "proposes a new Global Anatomic Staging System (GLASS), GLASS incorporates two novel and important concepts, the target arterial path (TAP) and estimated limb-based patency (LBP). Based on appropriate angiographic imaging, the TAP is defined by the treating surgeon or internationalist as the optimal arterial pathway to restore in-line (pulsatile) flow to the ankle and foot. LBP allows more direct comparison of anatomic outcomes across revascularization strategies in CLTI. The complexity of disease traversed by the TAP is integrated in the GLASS. Femoropopliteal (FP) and infrapopliteal (IP) arterial segments are individually graded on a scale of 0 to 4.(2)(3) Using a consensus based matrix, these segmental grades are combined into three overall GLASS (I-III) stages for the limb, reflecting the complexity of the disease with a proposed likelihood of immediate technical failure ' ITF " and 1 year "LBP " after endovascular intervention of " TAP ' (1)

Enrollment

36 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with infrainguinal CLTI

Exclusion criteria

  • Patients with concomitant Aorto-iliac lesions
  • Acute ischemia patients
  • Post Traumatic ischemia

Trial contacts and locations

1

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Central trial contact

Haitham Ali Hassan, MD; Ayman Elsayed Hassaballah, MD

Data sourced from clinicaltrials.gov

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