Glaucoma After Congenital And Infantile Cataract Surgery

Sun Yat-sen University

Status: Unknown

Conditions: Glaucoma; Congenital Cataract

Study type: Observational

Funder types: Other

Identifiers

NCT04131114

CCPMOH2016-China-0303

Details and patient eligibility

About

Pediatric patients who have undergone surgery for congenital or infantile cataracts have a risk of developing suspected glaucoma and glaucoma, but the current evidence does not address our understanding of the incidence and associated risk factors of suspected glaucoma/glaucoma for application in clinical standard care. Therefore, this study investigated the incidence of and risk factors for suspected glaucoma/glaucoma in patients who have undergone surgery for congenital/infantile cataracts.

Full description

A prospective longitudinal cohort study of pediatric patients who underwent surgery for congenital/infantile cataracts between January 2011 and December 2021 was performed.

Enrollment: 241 estimated patients

Sex: All

Ages: Under 10 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a diagnosis of congenital/infantile cataracts without any surgical intervention;
• age younger than 10 years;
• cataract surgery performed at the Zhongshan Ophthalmic Center after enrollment

Exclusion criteria

• a preoperative IOP above 21 mm Hg;
• the presence of any preoperative sign of glaucoma, such as corneal enlargement, corneal clouding, excessive optic nerve cupping, or a family history of glaucoma;
• the presence of ocular trauma or other abnormalities, such as microcornea, microphthalmia, persistent hyperplastic primary vitreous, Peters anomaly, congenital aniridia, Marfan syndrome, lens dislocation, retinitis pigmentosa, high myopia, fundus lesions, rubella, and Lowe syndrome.