Global Strain and Mechanical Dispersion May Predict Death and Ventricular Arrhythmias Better Than Ejection Fraction

University of Oslo (UIO)

Status: Enrolling

Conditions: Left Ventricular Function Systolic Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT02286908

2013/573/REK sør-øst

Details and patient eligibility

About

The aim of the study is to investigate if global strain and mechanical dispersion may predict death and ventricular arrhythmias better than ejection fraction(EF) in patients with myocardial infarction and heart failure regardless of cause.

Full description

1. The main aim of this study is to investigate if global strain and mechanical dispersion may predict death and ventricular arrhythmias better than left ventricular ejection fraction in patients with myocardial infarction and heart failure.
2. In patients who receive internal cardioverter defibrillator(ICD) the main aim is to investigate if mechanical dispersion may predict ventricular arrhythmias better than EF.

3. No interventions,only evaluation of the measurements obtained with transthoracic echocardiography.

4. Follow up for 3 years, extended from 3 to 5 years.

Enrollment: 3,100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients with

  1. myocardial infarction
  2. heart failure( defined as heart failure symptoms: reduced left ventricular function/ and or heart failure signs on chest x ray.
  3. planned for primary prophylactic ICD

• over 18 years of age

• Informed consent

Exclusion criteria