GLP-1: Acute Effects on Kidney Function in Healthy Men

Jeppe Skov

Status: Completed

Conditions: Kidney Functional

Treatments: Biological: Human GLP-1 (7-36) amide; Biological: Isotone NaCl

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01333163

VEKRM 29414

Details and patient eligibility

About

The purpose of this study is to investigate how Glucagon-Like Peptide 1 (GLP-1) affects kidney function in healthy young men. The hypothesis is that GLP-1 induces a positive effect on kidney hemodynamics.

Enrollment: 12 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy young men

Exclusion criteria

• Any chronic diseases

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 2 patient groups, including a placebo group

GLP-1

Active Comparator group

Treatment:

Biological: Human GLP-1 (7-36) amide

Placebo

Placebo Comparator group

Treatment:

Biological: Isotone NaCl