GLP-1 Receptor Targeting in Diabetic and Healthy Individuals (GLP-1-CPOP)

Radboud University Medical Center

Status: Completed

Conditions: Type 1 Diabetes

Treatments: Other: radiolabeled Exendin

Study type: Observational

Funder types: Other

Identifiers

NCT01825148

RUNMC-EX-BCM-2012

2012-000619-10 (EudraCT Number)

Details and patient eligibility

About

The purpose of the study is to determine whether there are differences in pancreatic uptake of the radiotracer between healthy individuals and patients with type 1 diabetes. If T1D patients have a markedly reduced uptake, the compound may be suitable for estimation of pancreatic beta cell mass, i.e. the cells in the pancreas that produce insulin.

Enrollment: 20 patients

Sex: All

Ages: 21 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• type 1 Diabetes

Exclusion criteria

• breast feeding
• pregnant

Trial design

20 participants in 2 patient groups

Type 1 Diabetes

Description:

patients with long standing T1D

Treatment:

Other: radiolabeled Exendin

Healthy volunteer

Description:

healthy volunteers with normal glucose tolerance

Treatment:

Other: radiolabeled Exendin