GLP-2 (Glucagonlike Peptide-2) and Blood Flow

Glostrup University Hospital, Copenhagen

Status: Completed

Conditions: Regional Blood Flow

Treatments: Other: Glucagonlike peptide

Study type: Interventional

Funder types: Other

Identifiers

NCT00540215

H-D-2007-0050

Details and patient eligibility

About

It is the study aim to investigate the effect of glp-2 on blood flow in humans. we wish to study eventual changes in renal blood flow, carotic blood flow and cardiac out put.

GLP-2 will be administered subcutaneously, and the effect monitored by doppler ultra sound scannings and cotinuesly measuring of cardiac out put and blood pressure.

The study will include 15 healhty volunteers, 10 wil receive 450 nmol GLP-2 and 5 will receive 1 ml of isotonic saline (as baseline reference).

Full description

se the above

Enrollment: 15 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 20-60
• Healthy
• No medication
• Not pregnant

Exclusion criteria

• All of the persons not meeting the abowe mentioned criteria

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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15 participants in 2 patient groups, including a placebo group

1

Active Comparator group

Description:

450 nmol GLP-2 SC

Treatment:

Other: Glucagonlike peptide

2

Placebo Comparator group

Description:

1 ml isotonic saline SC

Treatment:

Other: Glucagonlike peptide