GLUCOSAMINE/CHONDROITIN and PHYSICAL THERAPY EFFECTS ON OLDER POPULATION WITH KNEE OSTEOARTHRITIS

Muhammad salman, PT

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Combination Product: glucosamine chondritin & Physiotherapy; Other: Glucosamine Chondroitin

Study type: Interventional

Funder types: Other

Identifiers

NCT05321836

333

Details and patient eligibility

About

to see the effect of glucosamine chondratin sulfate with and without physiotherapy in knee osteoarthritis

Full description

it is a randomized control trail to evaluate the effectiveness of glucosamine chondratin sulfate alone and in combination with physiotherapy on knee osteoarthritis

Enrollment: 30 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age > 50 years with radiographic evidence of mild to moderate knee OA (Kellgren Lawrence grade II & III 20) who met the ACR clinical 21,
• radiographic classification criteria or confirmation of mild to moderate radiographic evidence of knee OA from a personal physician
• not currently participating in another intervention study

Exclusion criteria

• dementia (Mini-Mental State Examination [MMSE]< 24)
• active cancer other than skin cancer
• anemia (participants with an hematocrit (HCT)< 32 (or a hemoglobin below10) were excluded due to possible inability to adequately exercise or the increased potential for increased risk for serious adverse cardiovascular events)
• severe renal insufficiency (serum creat> 2)
• hepatic disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

control group

Active Comparator group

Description:

chondritin sulfate 1500/1200mg

Treatment:

Other: Glucosamine Chondroitin

experimental group

Experimental group

Description:

chondritin sulfate plus physiotherapy

Treatment:

Combination Product: glucosamine chondritin & Physiotherapy