Glucose:Fructose Versus Glucose Carbohydrate Ingestion and Endurance Performance

Nestlé

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: Mixture of glucose and fructose; Dietary Supplement: glucose

Study type: Interventional

Funder types: Industry

Identifiers

NCT02031783

13.09.PER

Details and patient eligibility

About

The primary objective is to show that multiple transportable carbohydrate ingestion is more effective in improving endurance performance compared to single transportable carbohydrate ingestion.

Enrollment: 74 patients

Sex: Male

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Males aged 18 to 60 years

• A history of competitive triathlon performance (≥ 2 years)

• Participation in at least four competitive triathlon events within the past 2 years

• Be in regular training for triathlon events

• A personal best time for a standard ½ Ironman race (1.9 km swim, 90 km cycle, 21.1 km run) in the last year of either:

  • ≤ 6 h 00 min, for men aged 18-40 years
  • or ≤6 h 05 min for men aged 40-50 years
  • or ≤6 h 20 min for men aged 50-60 years

• Alternatively, if not competed in ½ Ironman in the last year, at least one standard distance triathlon (1.5 km swim, 40 km cycle, 10 km run) within the last 12 months:

  • ≤2 h 13 min, for men aged 18-40 years
  • or ≤2 h 18 min for men aged 40-50 years
  • or ≤2 h 23 min for men aged 50-60 years

• Available to compete in the ½ Ironman events and complete all study requirements

• Experienced in using carbohydrate supplementation, as gels, bars, and drinks in training/racing, specifically at rates ≥60-90g/h)

• Experience of specific formulations may include both or only multiple and single transportable carbohydrates, thus a full assessment would be made prior to recruitment to ensure balance during randomization and account for any association with the primary outcome

• Obtained his (or his legal representative's) informed consent.

Exclusion criteria

• Failure to meet health requirements defined in the Health Questionnaire
• Prior known fructose intolerance
• Wheat intolerance or other precluding food or packaging-related allergies
• An existing injury affecting ability to race to best ability
• A chronic injury that may affect ability to complete the races
• Unable to carry out performance assessments and questionnaires correctly
• Unable to tolerate the treatment during the familiarization sessions
• Taking medications thought to interfere with the study outcomes
• Currently participating or having participated in another clinical study during the last four weeks prior to the beginning of this study

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

---

74 participants in 2 patient groups

mixture of glucose and fructose

Experimental group

Description:

mixture of glucose and fructose

Treatment:

Dietary Supplement: glucose

Glucose

Active Comparator group

Description:

Single glucose

Treatment:

Dietary Supplement: Mixture of glucose and fructose