Glucose in Dialysis Water in Diabetics With Chronic Renal Failure

Regional Hospital Holstebro

Status and phase: Completed; Phase 4

Conditions: Diabetic Nephropathies; Renal Failure, Chronic

Treatments: Procedure: Procedure

Study type: Interventional

Funder types: Other

Identifiers

NCT00438503

MED.RES.2007.02.EBP

Details and patient eligibility

About

The purposes are 1. to measure the effect of dialysis with glucose in dialysis water on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin and body temperature, and 2. to analyse the relationship between the changes in blood pressure and changes in vasoactive hormones

Full description

The relationship between blood pressure during dialysis treatment and vasoactive hormones are studied. This includes measurements of plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin

Enrollment: 18 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age > 18 years,
2. Both men and women,
3. Dialysis treatment for at least three month due to diabetic nephropathy

Exclusion criteria

1. Heart failure,
2. Lung insufficiency,
3. Chronic liver disease,
4. Malignant disease,
5. Nephrotic syndrome,
6. Lack of compliance,
7. Unwillingness to participate

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)