Glucose Metabolism After Partial Pancreatectomy

Seoul National University

Status: Completed

Conditions: Pancreatectomy; Hyperglycemia; Diabete Mellitus

Treatments: Diagnostic Test: oral glucose tolerance test

Study type: Observational

Funder types: Other

Identifiers

NCT04409171

SNUBH-GS-HBP6

Details and patient eligibility

About

This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.

Full description

Biochemical markers of glucose metabolism including oral glucose tolerance tests, fasting blood glucose, insulin, glucagon and HbA1c were performed on patients receiving pancreatectomy (pancreaticoduodenectomy and distal pancreatectomy). Tests were done preoperatively, postoperatively at 3 months, and at 1 year. The primary endpoints were the incidence and risk factors of new-onset and worsened DM after each type of pancreatectomy.

Enrollment: 224 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• partial pancreatectomy

Exclusion criteria

• total pancreatectomy
• incomplete testing
• follow-up loss
• death within 1 year

Trial design

224 participants in 2 patient groups

PD

Description:

pancreaticoduodenectomy

Treatment:

Diagnostic Test: oral glucose tolerance test

DP

Description:

distal pancreatectomy

Treatment:

Diagnostic Test: oral glucose tolerance test