Glucose Response From Antioxidant Rich Potato Chips

Purdue University

Status: Completed

Conditions: Glycemic Response

Treatments: Other: Crackers; Other: White potato chips; Other: Mountain Rose potato chips; Other: Purple Majesty potato chips

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02927015

055-043

Details and patient eligibility

About

Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.

Full description

Preclinical data obtained using an Caco-2 intestinal cell model and enzyme assays suggest phenolic-rich potato extracts decrease intestinal glucose transport. The aim is to determine if these effects extend to the the an in vivo situation. Specifically, the glycemic response following consumption of phenolic rich pigmented potatoes compared to white potatoes with lower phenolic content will be measured. Gastric emptying will also be measured to show the effects are in fact due to rate of carbohydrate digestion and intestinal glucose transport and not gastric emptying rate.

Enrollment: 11 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 18-25 non-smoker

Exclusion criteria

• BMI outside 18-25 smoker previous gastrointestinal disease or other disease

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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11 participants in 4 patient groups

Purple Majesty potato chips

Experimental group

Description:

Purple Majesty potato chips

Treatment:

Other: Purple Majesty potato chips

Mountain Rose potato chips

Experimental group

Description:

Mountain Rose potato chips

Treatment:

Other: Mountain Rose potato chips

White potato chips

Experimental group

Description:

White potato chips

Treatment:

Other: White potato chips

Crackers

Experimental group

Description:

Crackers

Treatment:

Other: Crackers