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Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients

University of Wisconsin (UW) logo

University of Wisconsin (UW)

Status and phase

Completed
Phase 4

Conditions

Hematopoietic Stem Cell Transplantion
Bone Marrow Transplantation

Treatments

Drug: glutamine popsicle
Drug: nutritional supplement

Study type

Interventional

Funder types

Other

Identifiers

NCT00204958
2003-222

Details and patient eligibility

About

Nutrition is an important part of the recovery process after having a head injury so that subjects can gain strength and fight off infection. Liquid nutrition formulas are often given to patients through a tube that has been placed into the intestines for feeding when they are unable to eat on their own. Some reports suggest that nutrition with extra amounts of the amino acid called glutamine may decrease infections and hospital stay in severely injured patients. The purpose of this study is to evaluate if giving extra amounts of an amino acid called glutamine with liquid nutrition formulas will decrease the risk of infection and length of stay in the intensive care unit after having a head injury.

Enrollment

50 estimated patients

Sex

All

Ages

4 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Males
  • Nonpregnant females
  • Receiving chemotherapy for BMT/HSCT

Exclusion criteria

  • Documented hepatic dysfunction
  • History of cirrhosis
  • History of acute renal failure (creatinine clearance < 25 mL/min)
  • Gastrointestinal malabsorptive disorder

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Factorial Assignment

Masking

Double Blind

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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