Glutathione and Health With Post-Polio Syndrome
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Details and patient eligibility
About
In this study, people who have symptoms of post polio will take oral glutathione supplements for three months. Their levels of fatigue, physical activity and sleep efficiency will be assessed.
Full description
Subjects will take a glutathione supplement by mouth for three months after an initial medical visit, blood draw and physical exam. There are four timepoints during the three months when subjects will fill out surveys and record food intake and sleep times in diaries for seven days. They will also wear a small device for seven days, a Sensewear monitor that records physical activity, body temperature and other measures.
After the fourth timepoint they will return to the medical center for another physical exam and blood draw. Physicians trained in physical medicine and rehabilitation will be monitoring the study.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Ability to walk 100 feet with usual assistive devices (ex. cane or walker)
- Having a function score of 18-32 when tested with the IPPS (Index of Post- Polio Sequelae). This will include people with post-polio symptoms in a very specific range of severity.
Exclusion criteria
- Having another serious medical condition (cancer, multiple sclerosis, etc.)or inflammatory disease (ie., lupus)
- Currently taking glutathione or other antioxidants
Trial design
Primary purpose
Allocation
Interventional model
Masking
20 participants in 1 patient group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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