Glycaemic Load and Pre-meal Insulin Doses in Type 1 Diabetes Patients (GLUT)

Federico II University

Status: Completed

Conditions: Type 1 Diabetes

Treatments: Other: Adjustment of pre-prandial insulin doses on the bases of carbohydrates content of the meal; Other: Adjustment of pre-prandial insulin doses on the bases of glycaemic load of the meal

Study type: Interventional

Funder types: Other

Identifiers

NCT01978704

37/13

Details and patient eligibility

About

The aim of this study is to compare the feasibility and the efficacy on short-term glucose control of pre-meal insulin doses adjustment made on the bases of the glycemic load or of the carbohydrates content of the meal in patients with type 1 diabetes mellitus treated with insulin pump

Enrollment: 9 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 1 diabetes treated by insulin pump

Exclusion criteria

• Preganncy

• HbA1c > 9%

  • Any serious acute or chronic illness a part diabetes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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9 participants in 2 patient groups

Glycaemic load

Experimental group

Treatment:

Other: Adjustment of pre-prandial insulin doses on the bases of glycaemic load of the meal

Carbohydrates content

Active Comparator group

Treatment:

Other: Adjustment of pre-prandial insulin doses on the bases of carbohydrates content of the meal