Glycated Hemoglobin Targets and Glycemic Control in Indonesian Diabetic Patients

Tarumanagara University

Status: Completed

Conditions: Diabetes Mellitus

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT03580226

APS001

Details and patient eligibility

About

This study aims to compare uric acid, lipid, and kidney profile along with management and complications of Indonesian diabetic patients with good and poor glycemic control based on glycated hemoglobin profile.

Full description

Adult patients (≥ 18 years of age) with type 2 diabetes which are diagnosed under ICD-10 coding of E-11 were included in this study. The inclusion criteria are patients with primary diagnosis of E11and have visited the clinic at least twice with a complete record of glucose, uric acid, lipid and kidney profile. Participants were grouped into 2 groups - good and poor glycemic control based on their glycated hemoglobin (HbA1c) levels. Good glycemic control is defined according to the American Diabetes Association and the Indonesian Association of Endocrinologists (PERKENI) cut off of HbA1c < 7.0.

Data such as age, sex, ethnic, education, BMI, glucose, uric acid, lipid, and kidney profile as well as comorbidities and type of drug used were collected from the patients' medical records. Comorbid conditions were defined as either concomitant hypertension, dyslipidemia, chronic kidney disease, hyperuricemia, or combinations of them as diagnosed in the medical records. Diabetic complications of interest include macrovascular (heart disease, stroke), microvascular (nephropathy, retinopathy, neuropathy) and a combination of both as well as infection (urinary tract infection, pneumonia). These complications were also based on the medical records. Management modalities included were lifestyle modification, use of oral antidiabetic medications or insulin, or both.

Enrollment: 55 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Type 2 Diabetes
• Must have visited the clinic at least twice, one before and one post-therapy

Exclusion criteria

• Type 1 Diabetes, Gestational Diabetes and other secondary diabetes types
• Unavailability of HbA1c results - pre and post-therapy
• Incomplete records of glucose, uric acid, lipid and kidney profile, comorbidities and management.

Trial design

55 participants in 2 patient groups

Good glycemic control

Description:

Good glycemic control is defined according to the American Diabetes Association and the Indonesian Association of Endocrinologists (PERKENI) cut off of HbA1c \< 7.0.

Treatment:

Other: No intervention

Poor glycemic control

Description:

Poor glycemic control is defined according to the American Diabetes Association and the Indonesian Association of Endocrinologists (PERKENI) cut off of HbA1c \>= 7.0.

Treatment:

Other: No intervention