Glycemic and Insulinemic Responses of Low-Carbohydrate Snack Foods

TC Erciyes University

Status: Completed

Conditions: Healthy

Treatments: Other: Snacks with Cheese; Other: Glucose Solution Second Repeat; Other: Glucose Solution First Repeat; Other: Spicy Crackers; Other: Blueberry Cake

Study type: Interventional

Funder types: Other

Identifiers

NCT04175496

ND

Details and patient eligibility

About

The aim of this study is develop recipes containing CHO less than ICR, prepare new snacks alternatives that could be consumed without need for additional insulin doses, and evaluate the glycemic and insulinemic responses of these recipes. A randomized crossover trial will include 15 healthy adults aged 19-30 years. All participants will consume 3 test foods and reference food (glucose solution, 2 times) in a random order. Blood samples will be collected at time points 0,15, 30, 45, 60, 90 and 120 min. Glucose and insulin analyzes will be performed from blood samples. The results of these time points will be marked on the chart and the incremental area under the curve (iAUC) will be calculated for both glucose and insulin.

Enrollment: 10 patients

Sex: All

Ages: 19 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteer
• Normal body weight (18.5-25 kg / m2 BMI)
• 19-30 years old

Exclusion criteria

• use of tobacco,
• weight change of >5 kg in the last 3 months
• the presence of any chronic disease or lactose intolerance,
• regular medicine use,
• pregnancy or lactation,
• performing competitive sports or endurance sports,
• fasting plasma glucose concentration >100 mg / dL,
• the presence of eating disorder,
• sensitivity or allergies to any food that used in the study

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

Test Foods

Experimental group

Description:

Blueberry Cake, Snack with Cheese and spicy Crackers will be used as test foods.

Treatment:

Other: Snacks with Cheese

Other: Blueberry Cake

Other: Spicy Crackers

Reference Food

Experimental group

Description:

Glucose solution will use as reference food.

Treatment:

Other: Glucose Solution Second Repeat

Other: Glucose Solution First Repeat