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Glycemic Control and Iron Status in Diabetic Pregnancies - a Study of New Markers

H

Helse Stavanger HF

Status

Completed

Conditions

Diabetes Mellitus Pregnancy

Study type

Observational

Funder types

Other

Identifiers

NCT03330951
SUS-ID580

Details and patient eligibility

About

This is an observational study at the Obstetrical outpatient clinic at Stavanger University Hospital. The main goal is to compare the current marker of glycemic control (glycated hemoglobin A1c, HbA1c) with glycated albumin in pregnancies with pregestational diabetes mellitus.

Women with diabetes are at increased risk for adverse pregnancy outcomes. With improved glycemic control, the risk decreases. Glycated albumin is suggested to be a better marker for monitoring glycemic control in pregnancies because it reflects blood glucose for a shorter period than HbA1c (3 versus 8-12 weeks). Other studies have shown that HbA1c increases in pregnancy because of iron deficiency. The investigators want to investigate HbA1c, glycated albumin and iron status in diabetic pregnancies. The investigators will compare HbA1c and glycated albumin throughout pregnancy with the patient's own blood glucose measurements or data from CGM (continuous blood glucose monitoring). Blood samples for HbA1c and glycated albumin will be taken 6 times during pregnancy (week 12, 20, 24, 28, 32, 36).

Enrollment

41 patients

Sex

Female

Volunteers

No Healthy Volunteers

Inclusion criteria

  • pregestational diabetes mellitus
  • singleton pregnancy
  • follow-up at Stavanger University Hospital in pregnancy

Exclusion criteria

  • gestational diabetes
  • twin pregnancies

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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