Glycemic Control Following Occupational Work in a Hot Environment

Loughborough University

Status: Not yet enrolling

Conditions: Plasma Glucose Following Prolonged Heat Exposure

Treatments: Other: Hot environment; Other: Temperate condition

Study type: Interventional

Funder types: Other

Identifiers

NCT06982612

LEON21544

Details and patient eligibility

About

Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration. While the physiological impacts of heat exposure are well-documented, its effects on glycemic control remain less understood. Given the rising global temperatures due to climate change and the increasing prevalence of metabolic disorders such as obesity and type 2 diabetes, it is essential to investigate how heat exposure during work influences glycemic regulation. Understanding these interactions will help inform future occupational health guidelines and metabolic health recommendations in physically demanding industries.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female
• Generally fit and healthy
• Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week

Exclusion criteria

• Under 18 or 45 and over,
• any morbidity or medication that might influence carbohydrate/fat metabolism (i.e., liver/renal/cardiovascular disease) or cycling ability (musculoskeletal injury etc),
• coagulation or bleeding disorders,
• blood-borne illness,
• heart conditions,
• congenital heart disease,
• uncontrolled exercise-induced asthma,
• smoking (including vaping),
• allergies to the products used in the study,
• dieting or restrained eating behaviours.
• Females with amenorrhea would be an exclusion criteria.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Hot condition

Experimental group

Description:

Light exercise in a hot environment with ad libitum water intake

Treatment:

Other: Hot environment

Temperate condition

Experimental group

Description:

Light exercise in a temperate environment with ad libitum water intake

Treatment:

Other: Temperate condition