Glycosaminoglycans During Septic Shock - a Temporal Study (GAGS)

Region Skane

Status: Withdrawn

Conditions: Septic Shock

Study type: Observational

Funder types: Other

Identifiers

NCT00814112

GAGS 293/2008

Details and patient eligibility

About

We have previously shown that the plasma level of glycosaminoglycans (GAG) in septic shock patients are elevated compared to controls. The purpose of this study is to investigate the temporal dynamic of the blood level of GAG in ten septic shock patients. In addition, to assess the kinetics of GAG during septic shock we examine the liver function by galactose elimination capacity as well as excreted urinary GAG.

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 2 out of 4 SIRS criteria, where the circulatory criteria must be fulfilled
• Clinical sepsis is suspected
• Informed consent from relative
• Study subject must be over 18 years old

Exclusion criteria

• Pregnancy
• >24h post sepsis diagnosis
• Ongoing oral or intravenous cortisone treatment for more than one month.
• Malignancy with metastasis

Trial design

0 participants in 2 patient groups

1 septic shock

Description:

septic shock, ICU

2 controls

Description:

matched controls