Glypican4 and CTRP5 in Metabolic Syndrome and the Effect of Exercise on These Adipokines

Korea University

Status: Completed

Conditions: Obesity; Metabolic Syndrome

Treatments: Behavioral: 3months Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01688622

KoreaSO_Exercise

Details and patient eligibility

About

Glypican4, CTRP3, CTRP5 are emerging novel adipokines mediating obesity and inflammation related disorders. RBP4 and adiponectin are well known important adipokines. Therefore, we examine the circulating levels of theses adipokines in the subjects with or without metabolic syndrome. Furthermore, we tried to clarify the effect of exercise on the circulating these adipokines.

Enrollment: 90 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women between 30 and 60 years of age who had a body mass index (BMI) more than 25 kg/m2
• The subjects of metabolic syndrome and age, gender matched non metabolic syndrome among the participants of Korean SO Study (KSOS) study, which is an ongoing epidemiologic study supported by the Korea Science and Engineering Foundation

Exclusion criteria

• participants had a history of cardiovascular disease
• any type of diabetes
• stage 2 hypertension
• malignant disease, severe renal, or hepatic disease
• Subjects taking medications that might affect body weight or body composition

Trial design

90 participants in 1 patient group

Exercise

Other group

Description:

obese women who are volunteers for the 3 months exercise programs

Treatment:

Behavioral: 3months Exercise