Goal-directed Analgesia Using ANI During General Anesthesia in Children With Moyamoya Disease

Seoul National University

Status: Enrolling

Conditions: Pain

Treatments: Device: ANI (Analgesia/Nociception Index) monitoring; Drug: Sufentanil; Device: standard monitoring

Study type: Interventional

Funder types: Other

Identifiers

NCT05672212

2211-149-1381

Details and patient eligibility

About

Analgesia Nociception Index (ANI) has been proposed for the evaluation of the nociception-antinociception balance in the perioperative period. In pediatric patients with Moyamoay disease, where the management of analgesia may be rendered difficult by pharmacological changes, we hypothesised that the monitoring of analgesia with ANI would reduce intraoperative opioid consumption during EDAS surgery.

Enrollment: 40 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pediatric patients receiving EDAS surgery for Moyamoya disease

Exclusion criteria

• ASA (American society of anesthsiologists classification) 4-5
• Emergency surgery
• patients with chronic pain on medication

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

ANI (Analgesia/Nociception Index) monitoring

Experimental group

Treatment:

Drug: Sufentanil

Device: ANI (Analgesia/Nociception Index) monitoring

Standard monitoring

Active Comparator group

Treatment:

Drug: Sufentanil

Device: standard monitoring