Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries

Zagazig University

Status: Not yet enrolling

Conditions: ERAS; Hypovolemia; Surgical Shock; Fluid Overload; Anesthesia

Treatments: Procedure: Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index; Procedure: standard fluid management

Study type: Interventional

Funder types: Other

Identifiers

NCT06133257

11122

Details and patient eligibility

About

Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.

Full description

To overcome these problems and avoid the complications of over or underhydration, we use the Goal-directed fluid therapy(GDFT) guided by Inferior vena cava(IVC) collapsibility index approach in which dynamic parameters of volume responsiveness as a guide for fluid therapy. This will ensure that the fluids given were deficient from the circulation and improve the recovery of the patients according to enhanced recovery after surgery(ERAS) protocols.

Enrollment: 52 estimated patients

Sex: All

Ages: 21 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient's acceptance.
• Patients planned for elective lower limb surgery under spinal anesthesia.
• Both sexes
• Body Mass Index(BMI): <35
• Age: 21 ~ 65 years
• American Society of Anesthesiologists(ASA) Physical Status Classification System: Class I & II
• Duration of surgery 2~3 hours

Exclusion criteria

• Advanced kidney, liver, respiratory or cardiovascular disease.
• Contraindication for spinal anesthesia.
• Patients shifted to general anesthesia for any reason.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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52 participants in 2 patient groups

GD Group

Active Comparator group

Description:

Patients will take oral clear fluids with carbohydrates content 2 hours preoperatively and intraoperative fluid intake will be guided by Inferior vena cava(IVC) diameter.

Treatment:

Procedure: Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index

C Group

Active Comparator group

Description:

the standard fluid management group patients will be fasting 6 hours preoperatively and will receive intraoperative fluid in standard manner.

Treatment:

Procedure: standard fluid management