Goal Directed Hemodynamic Management and Renal Outcome After Renal Transplant Surgery (IROR)

Technical University of Munich

Status: Terminated

Conditions: Renal Transplant Surgery

Treatments: Device: PiCCO® Monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT01485432

IROR

Details and patient eligibility

About

This study is designed to compare the incidence of delayed graft function in patients following renal transplant surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using PiCCO) and a control group.

Full description

Volume assessment and management during renal transplantation is one of the most challenging problems the anesthetist has to deal with. It seems sensible that individualized volume management and hydration therapy during the operation and during the stay at the intensive care unit could improve perfusion of the transplanted organ resulting in a better transplant function. Aim of this study is to investigate the impact of a goal directed hemodynamic management on incidence of delayed graft function (DGF) after renal transplant surgery.

Therefore patients will be randomized in one of two groups, the PiCCO group with goal directed hemodynamic management during operation and during the ICU-stay and the control group with hemodynamic management performed according to heart rate, blood pressure and central venous pressure.

Enrollment: 1 patient

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Renal Transplant Surgery
• Age ≥ 65 years
• Written informed consent

Exclusion criteria

• Contraindications for an arterial line in the femoral artery:

  • stents
  • bypasses
  • severe peripheral artery occlusive disease

Trial design

1 participants in 2 patient groups

P group

Description:

Group P: Fluid Management according to measurements with PiCCO®

Treatment:

Device: PiCCO® Monitoring

C group

Description:

Group C: Conventional fluid management