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Goal-orientated Coagulation Management in Hypothermic Cardiac Arrest Surgery

University Hospital Basel logo

University Hospital Basel

Status

Completed

Conditions

Cardiac Arrest

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Cardiac surgery including hypothermic cardiac arrest (HCA) commonly involves perioperative transfusion of allogeneic blood products which is associated with increased morbidity and mortality. In this retrospective analysis, the investigator aimed to evaluate the effect of a thromboelastometry-guided treatment algorithm promoting fibrinogen concentrate as first line hemostatic agent on the perioperative use of allogeneic blood products.

Full description

The investigators will analyze the data of patients undergoing elective and emergent surgical procedures involving the ascendent aorta and/or the aortic arch with the help of HCA from January 2009 to June 2011.

The investigators will collect and document baseline characteristics, the use of thromboelastometry, thromboelastometric data, and perioperative laboratory data. In addition, the investigators will evaluate perioperative bleeding from mediastinal drainages, perioperative use of blood and hemostatic products, and the adverse events within the hospitalisation including re-exploration, renal impairment, myocardial infarction, severe brain injury, and death.

Enrollment

200 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Cardiac surgery with HCA due to pathology of the proximal aorta from January 2009 until June 2011

Exclusion criteria

  • none

Trial design

200 participants in 1 patient group

Cardiac surgery with HCA
Description:
Patients undergoing cardiac surgery with the help of hypothermic cardiac arrest for pathologies of the proximal aorta

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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