Goal-orientated Therapy of Perioperative Disturbance in Hemostasis in Cardiac Surgery

University Hospital Basel

Status: Completed

Conditions: Coronary Artery Bypass Graft Triple Vessel; Blood Coagulation Disorders

Study type: Observational

Funder types: Other

Identifiers

NCT00516126

194/06

Details and patient eligibility

About

Aim of this study is to investigate whether patients preoperatively treated with acetylsalicylic acid and/or clopidogrel have fewer perioperative bleeding and lower amounts of blood substitution when managed by ROTEM (whole blood coagulation analyzer) and MULTIPLATE (thrombocyte function analyzer).

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• written consent

Exclusion criteria

• no written consent

Trial design

200 participants in 2 patient groups

Point-of-Care managed

Description:

This arm includes all patients in which the hemostatic therapy is guided by POC devices e.g. MULTIPLATE (a platelet function analyzer) or ROTEM (thromboelastometry)

Conventional hemostasis lab managed

Description:

This arm includes all patients in which the hemostatic therapy is guided by conventional hemostasis laboratory data e.g. INR, aPTT, fibrinogen concentration, platelet count but no POC devices e.g. MULTIPLATE (a platelet function analyzer) or ROTEM (thromboelastometry)