Golgi Protein for HCC Diagnosis

Ain Shams University

Status: Completed

Conditions: Screening for Hepatocellular Carcinoma

Treatments: Diagnostic Test: Serum Golgi Protein 73

Study type: Observational

Funder types: Other

Identifiers

NCT03039322

914

Details and patient eligibility

About

This case-control study was conducted on 90 patients who were equally divided into two groups. Group 1 included 45 patients with HCV-related chronic liver disease without clinical or radiological evidence of HCC (control group), and Group 2 included 45 patients diagnosed to have HCC by Triphasic abdominal CT (patient group). Serum AFP and GP73 were measured using ELISA technique

Enrollment: 90 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients were older than 18 years.

Exclusion criteria

• patients with hepatic focal lesions not due to HCC such as Hemangioma, Hepatic cyst, and liver metastases; patients infected with HIV; patients with any autoimmune disease; or patients with metastatic disease.

Trial design

90 participants in 2 patient groups

HCC

Treatment:

Diagnostic Test: Serum Golgi Protein 73

liver cirrhosis No HCC

Treatment:

Diagnostic Test: Serum Golgi Protein 73