GON-block in Chronic Migraine: a Randomized, Double- Blind, Placebo-controlled Study (DHC-GON-1)

J

Jakob Møller Hansen, MD.

Status and phase

Unknown
Phase 4

Conditions

Chronic Migraine

Treatments

Drug: Betamethasone and local anesthetic

Study type

Interventional

Funder types

Other

Identifiers

NCT02686983
DHC-GON-1

Details and patient eligibility

About

Infiltration of the greater occipital nerve (GON) with local anaesthetics and corticosteroids is a treatment option for cluster headache. Corticosteroids may be helpful in reducing the pain intensity and frequency in chronic migrtaine. This RCT is set up to assess efficacy and safety of sub-occipital steroid injections with local anesthetic in patients with chronic migraine.

Full description

Infiltration of the greater occipital nerve (GON) with local anaesthetics and corticosteroids is a treatment option for cluster headache. In general, there is a marked paucity of evidence concerning GON blocks in migraine. Corticosteroids may be helpful in reducing the pain intensity and frequency in these patients. This is an RCT to assess efficacy and safety of sub-occipital steroid injections with local anesthetic in patients with chronic migraine.

Enrollment

34 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Chronic migraine

Exclusion criteria

  • Medication overuse headache

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Triple Blind

34 participants in 2 patient groups, including a placebo group

Active
Experimental group
Description:
Betamethasone and local anesthetic.
Treatment:
Drug: Betamethasone and local anesthetic
Placebo
Placebo Comparator group
Description:
Saline with local anesthetic.
Treatment:
Drug: Betamethasone and local anesthetic

Trial contacts and locations

1

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Central trial contact

Jakob Møller Hansen

Data sourced from clinicaltrials.gov

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