Gonadal Function in Thalassemic Patient

Sohag University

Status: Not yet enrolling

Conditions: Thalassemia Majors (Beta-Thalassemia Major)

Treatments: Diagnostic Test: serum inhibin B serum INSL3 serum AMH

Study type: Observational

Funder types: Other

Identifiers

NCT07288762

Soh-Med-25-9-18MS

Details and patient eligibility

About

Patient with transfusion depandant beta thalassemia with accumulation of iron in their body affect pituitary gland and gonades lead to impaired their functions .

Full description

detection of any abnormalities in pituitary gland hormones ( FSH , LH , serum prolactin ) gonadal hormones ( serum testesterone , antimullerian hormone , INSL3 , inhibin B hormone )

Enrollment: 80 estimated patients

Sex: Male

Ages: 10 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• transfusion depandant beta thalassemia
• age 10 to 18 year old age

Exclusion criteria

• age below 10 year old age or above 18 year old age
• associated with another disease

Trial design

80 participants in 1 patient group

group 1 transfusion depandant beta thalassemia

Description:

transfusion depandant beta thalassemia 10 - 18 years old age gonadal function assesment

Treatment:

Diagnostic Test: serum inhibin B serum INSL3 serum AMH