Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes

Tel Aviv Sourasky Medical Center

Status: Completed

Conditions: Mood Disorders

Treatments: Procedure: IVF procedure

Study type: Observational

Funder types: Other

Identifiers

NCT01032421

04-284

Details and patient eligibility

About

The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment. The secondary goal of this study is to explore psychological profiles and coping mechanisms of women undergoing IVF, and to identify the ones that are associated with successful psychological adaptation to the process and a successful biological outcome.

Enrollment: 100 estimated patients

Sex: Female

Ages: Under 42 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Admitted for their first or second IVF cycle;
2. Demonstrated sufficient communication skills and level of understanding in the Hebrew language;
3. signed an informed consent;
4. Were under the age of 42;
5. Were not suffering from endometriosis or male factor in patients who underwent testicular sperm extraction (TESE);
6. Were not under psychotherapeutic or psychopharmacological treatment. The accepted indications for the IVF included a female factor, male factor or unexplained infertility.

Exclusion criteria

1. All others.

Trial design

100 participants in 1 patient group

GNRH

Description:

Observational (IVF is not done as part of the study)

Treatment:

Procedure: IVF procedure