Graded Activity Training and Task- Oriented Training on Post-Stroke Fatigue

Riphah International University

Status: Enrolling

Conditions: Post-Stroke Fatigue

Treatments: Other: Task-Oriented Training; Other: Graded Activity Training

Study type: Interventional

Funder types: Other

Identifiers

NCT06846177

Sahar Khalid

Details and patient eligibility

About

The aim of this randomized controlled trial is to determine the effects of Graded Activity Training and Task Oriented Training on Fatigue in Post-Stroke Patients. Until now there is very limited work found on fatigue so this will increase quality of life in stroke patients and potentially reduce burden on healthcare system.

Full description

Post stroke fatigue (PSF) is one of the most common outcomes of stroke. PSF is defined as "overwhelming feeling of exhaustion or tiredness" as a result of stroke PSF is an undesirable outcome by which patient's ability in study participation, adherence to medication and effectiveness of rehabilitation decrease which is unrelated to exertion, and does not typically improve with rest. Prevalence rate of PSF ranges between 25% and 85% One out of two stroke survivors experience post-stroke fatigue. The relationship between physical deconditioning and fatigue is bidirectional there was a negative relationship between fatigue and aerobic fitness in chronic stroke. PSF may arise from physical deconditioning (physical fatigue). Therefore, improving physical endurance through physical activity training could potentially reduce fatigue complaints.

The rationale of this study is to determine how task-oriented training and graded activity training effect stroke patient's levels of fatigue and to develop an improved fatigue management intervention protocol. This study will also determine effects of how both interventions affect Mobility and Gait. By doing so, we can identify a more effective PSF intervention plan, which will help reduce the burden on the healthcare system and will lessen strain on caregivers and in turn enhance patient quality of life.

Enrollment: 20 estimated patients

Sex: All

Ages: 40 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Both male and female of age 40 to 60 years.
• Patient with both ischemic or hemorrhagic stroke.
• Patient with both right and left hemiplegia.
• Checklist Individual (CIS-F) fatigue score of 40 or more.
• Patients who had sustained a stroke more than 4 months before recruitment.
• Patients who can independently walk for 10 meters (about 33 feets)

Exclusion criteria

• Patients with severe comorbid health conditions (such as cardiac diseases, pulmonary diseases like COPD, Orthopedic Conditions Arthritis, joint replacements).
• Patients with uncontrolled diabetes, hypertension, Depression and Anxiety.
• Patients who are not willing to participate.
• Patient with any medications that can affect their ability to engage in physical training program like Antidepressants, Beta-Blockers, corticosteroids etc.
• Pregnant women.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

20 participants in 2 patient groups

Graded Activity Training

Experimental group

Description:

Graded Activity Training

Treatment:

Other: Graded Activity Training

Task Oriented Training

Active Comparator group

Description:

Task Oriented Training

Treatment:

Other: Task-Oriented Training