Grading Scale of Vitreous Haze in Patients With Uveitis Using Ultrasonography

University of Nebraska

Status: Withdrawn

Conditions: Uveitis

Treatments: Device: Ultrasonography B-scan

Study type: Interventional

Funder types: Other

Identifiers

NCT02311192

0583-14-EP

Details and patient eligibility

About

This study is aimed at creation and validation of a vitreous haze scoring system using ultrasonography B-scan of the eye. Images will be obtained from patients with uveitis and quantification of inflammation will be done to create the scoring scale.

Full description

Patients with uveitis may present with Vitreous Haze (VH) resulting in obscuration of fundus details. VH is composed of cells and protein exudation and results in decrease visual acuity.The degree of VH is an important indicator of disease activity, severity and response to therapy in patients with uveitis. Color fundus images are commonly used to objectively document VH.

Sex: All

Ages: 19 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Ability to provide written informed consent and comply with study assessments for the full duration of the study

  • Age 18 -90 years
  • Diagnosis of uveitis

Exclusion criteria

• • Patients with posterior segment complications including retinal detachment, choroidal detachment or hemorrhage

  • Patients with any intraocular foreign body or displaced intraocular lens
  • Patients with silicon oil filled eye or with gas tamponade.
  • Patients with vitreous hemorrhage
  • Patients with media opacity including visually significant cataract that precludes grading of VH based on fundus photography

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Ultrasonography B-scan

Experimental group

Description:

Patients of uveitis who are included in the study will be imaged using ultrasound B-scan

Treatment:

Device: Ultrasonography B-scan