Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts: Randomized Controlled Clinical Trial

Cairo University (CU)

Status: Enrolling

Conditions: Bone Loss, Alveolar

Treatments: Procedure: dental implant with bone augmentation

Study type: Interventional

Funder types: Other

Identifiers

NCT06653868

per631

Details and patient eligibility

About

In patients with a single non restorable tooth, does filling the peri-implant buccal gap with alloplastic sticky grafts result comparable results compared to xenogenic sticky grafts?

Full description

The buccal aspect of the dental implant has great importance, especially in the aesthetic zone, because the buccal bone is very thin especially in the anterior maxilla and its resorption can result in recession of the soft tissue. A gap occurs in immediately placed implant due to discrepancy between the dimensions of the extraction socket and the implant. Augmentation of the buccal gap decreases the amount of buccal bone resorption and soft tissue recession . Filling the peri-implant defects has been widely discussed to prevent further bone loss. The use of biologic materials such as platelet rich fibrin can enhance the quality of alloplastic bone grafts to give comparable effect when compared to xenogenic grafts.

Enrollment: 20 estimated patients

Sex: All

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with healthy systemic condition (Mazzotti et al., 2023).

2. Age from 20-50 years old

3. Patients must be free of any systemic disease which could influence the surgical procedure.

4. Tooth involved in the esthetic zone.

5. Sufficient hard and soft tissue volume in vertical and buccolingual direction

6. Natural teeth adjacent to the involved tooth will be required to be free from infection.

7. Controlled oral hygiene.

8. Indication for tooth extraction included (Degidi et al., 2012);

   • Endodontic failures
   • Untreatable caries
   • Non- restorable teeth
   • Vertical root fracture
   • Remaining roots

Exclusion criteria

• 1.Pregnant females 2.Smokers (Khuller, 2009) 3.Unmotivated and uncooperative patients with poor oral hygiene 4.Patients with habits that may compromise the longevity and affect the result of the study as alcoholism or parafunctional habits.

5.Presence of acute dento-alveolar infection.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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20 participants in 2 patient groups

immediate implant placement surgery with filling the gap distance with alloplastic sticky graft

Experimental group

Description:

immediate implant placement surgery with filling the gap distance with injectable platelet rich fibrin combined with alloplast.

Treatment:

Procedure: dental implant with bone augmentation

immediate implant placement surgery with filling the gap distance with xenogenic sticky bone

Experimental group

Description:

immediate implant placement surgery with filling the gap distance with injectable platelet rich fibrin combined with xenograft.

Treatment:

Procedure: dental implant with bone augmentation