Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy

Assiut University

Status and phase: Unknown; Phase 4

Conditions: Nausea and Vomiting, Postoperative

Treatments: Drug: Granisetron

Study type: Interventional

Funder types: Other

Identifiers

NCT04899817

Antiemetics in lab cholecystec

Details and patient eligibility

About

Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy

Full description

Post operative nausea and vomitting is Avery common complication of laparoscopic surgery in that study we will compare between granisteron and metoclopramide as aprophlaxis against post operative nausea and vomitting

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• both sexes Age between 18 and 60 years ASA1 2 3 Lap cholecystectomy under general anesthesia

Exclusion criteria

• patients refusal Pregnancy and breastfeeding Hepatic or renal disease ASA4 5 Allergy to the drug

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Group G

Active Comparator group

Description:

will receive granisteron 1mg after induction of general anesthesia

Treatment:

Drug: Granisetron

Group C

Placebo Comparator group

Description:

Will receive metoclopramide 10 mg after induction of general anesthesia

Treatment:

Drug: Granisetron