GRAPE • Glycemic Response of Amylopectin Containing Drinks

Arizona State University (ASU)

Status: Terminated

Conditions: Glycemic Index

Treatments: Dietary Supplement: Liquid Dextrose; Dietary Supplement: Energy smart Carbohydrate blend; Dietary Supplement: Carbohydrate drink

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03916692

FP00016578

Details and patient eligibility

About

To quantify the glycemic index of the SP energy-smart-based nutrition supplement and the SP Glucose-support formula as compared to a glucose drink. We hypothesized that both the energy-smart-based nutritional supplement and the SP Glucose-support formula will have low glycemic index.

The aim of the study is to quantify the glycemic index of the SP energy-smart-based nutrition supplement and the SP Glucose-support formula as compared to a glucose drink. We hypothesized that both the energy-smart-based nutritional supplement and the SP Glucose-support formula will have low glycemic index.

Full description

Subjects: 9 non-diabetic (HbA1c < 6.5) males aged 30-55 years with body mass indices ranging from 27.5 to 35 kg∙m-2. Individuals with impaired glucose tolerance will be included as long as they are not diagnosed with diabetes and their HbA1c is less than 6.5.

Preliminary Testing: Medical history, weight, height, body composition via dual x-ray absorptiometry (DXA) and glycosylated hemoglobin (HbA1c) measurement.

Protocol: After a 10-hour overnight fast, subjects will complete 3 experimental visits in which they will ingest one of three beverages in a randomized order. During experimental visits subjects will either be given the following 3 experimental drinks:

• Full SP-glucose balance formula (200 kcal)
• Energy smart carbohydrate blend (50 g, 200 kcal)
• Liquid dextrose solution in the form of TRUTOL ® Glucose Tolerance Test Beverage (50 g, 200 kcal)

Enrollment: 15 patients

Sex: Male

Ages: 30 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 27.5 to 35 kg∙m-2

Exclusion criteria

• Diagnosed diabetes
• HbA1c > 6.5
• competitive athletes
• body weigh change > 3kg during last month

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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15 participants in 3 patient groups

Standard Process - glucose balance

Experimental group

Description:

Standard Process - glucose balance formula (200 kcal)

Treatment:

Dietary Supplement: Carbohydrate drink

Energy smart Carbohydrate blend

Experimental group

Description:

Energy smart carbohydrate blend (50 grams, 200 kcal)

Treatment:

Dietary Supplement: Energy smart Carbohydrate blend

Liquid Dextrose Control

Active Comparator group

Description:

Liquid dextrose solution in the form of TRUTOL ® Glucose Tolerance Test Beverage (50 grams, 200 kcal)

Treatment:

Dietary Supplement: Liquid Dextrose