Graves' Orbitopathy and Hypercholesterolemia (GOCol)

University of Pisa

Status: Completed

Conditions: Graves' Ophthalmopathy; Hypercholesterolemia

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02721992

GOCol

Details and patient eligibility

About

The investigators have recently observed retrospectively that the occurrence of Graves' Orbitopathy in patients with Graves' disease is less frequent in patients with normal cholesterol levels, in line with another recent observation suggesting that statins play a protective role in Graves' patients from developing Graves' Orbitopathy. The present study is designed in order to investigate the possible association between Graves' Orbitopathy and high cholesterol level as well as the relation between Graves' Orbitopathy degree and high cholesterol level

Enrollment: 250 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Graves' disease with Graves' Orbitopathy
2. Graves' disease without Graves' Orbitopathy

Exclusion criteria

1. Previous treatment with radioiodine
2. Previous treatment with thyroidectomy

Trial design

250 participants in 2 patient groups

Graves' Disease

Description:

Patients with Graves' disease, without Graves' Orbitopathy

Treatment:

Other: No intervention

Graves' Orbitopathy

Description:

Patients with Graves' disease, with Graves' Orbitopathy

Treatment:

Other: No intervention