Greater Occipital and Supraorbital Nerve Blockade in Migraine Patients

Republic of Turkey Ministry of Health

Status: Completed

Conditions: Migraine Disorders

Treatments: Procedure: Saline injections; Procedure: Lidocaine injections

Study type: Interventional

Funder types: Other

Identifiers

NCT03435185

2014/514/85/5

Details and patient eligibility

About

The investigators aimed to evaluate the efficacy of greater occipital nerve and supraorbital nerve blockade with local anesthetics for the preventive treatment of migraine without aura.

Full description

A mixture of 1 ml 2% lidocaine and 0.9% 1 ml saline was injected bilaterally to GON and SON in the blockade patients. Placebo patients received 2 ml 0.9% saline in the same way. Patients were blinded to kind of injection.

Enrollment: 103 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Lack of benefits 1 year from preventive treatment or intolerance to their treatments.
• 18 ≥ years old
• Migraine without aura for more than 1 year, minimum of two or more migraine attacks per month.

Exclusion criteria

• Patients with any chronic illness, medication overuse headache, a history of cranial and cervical surgery
• Allergies to local anesthetics
• Hemorrhagic diathesis
• Alcohol or drug abuse

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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103 participants in 2 patient groups, including a placebo group

Blockade Group

Active Comparator group

Description:

Lidocaine injections. Procedure. Grater occipital nerve and supraorbital nerve were blocked with %2 lidocaine. These injections were repeated weekly for three weeks. After treatment was completed, patients were followed up for 2 months at the polyclinic to assess the clinical response.

Treatment:

Procedure: Lidocaine injections

Placebo Group

Placebo Comparator group

Description:

Saline injections. Procedure. Grater occipital nerve and supraorbital nerve were injected with saline.These injections were repeated weekly for three weeks. After treatment was completed, patients were followed up for 2 months at the polyclinic to assess the clinical response.

Treatment:

Procedure: Saline injections