Green Tea, High in Epigallocatechin Gallate (EGCG) and Postprandial Fat Oxidation
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About
The body of evidence regarding the health benefits of green tea has grown considerably during the last decade and includes antioxidant properties, anti- cancer, anti-obesity and anti-diabetes effects. There has been evidence that green tea extract favorably affect body weight and body fat and has positive effects on blood glucose control
Aim of this study is to investigate the short term effect (3-day)of TEAVIGO (high in the catechin EGCG) on postprandial fat oxidation during different phases of the postprandial period in overweight subjects. Secondly, in a subset of volunteers changes in lipolysis and glucose metabolism will be studied in skeletal muscle and adipose tissue.
Enrollment
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Volunteers
Inclusion criteria
- Age between 20 and 50 y
- BMI 25.0-29.9 kg/m2
- Normal fasting glucose <6.1 mmol/L
- Blood pressure (systolic blood pressure 100-150 mmHg, diastolic blood pressure 60-90 mmHg)
- Weight stable in last 3 months (±2 kg)
Exclusion criteria
- pregnant, lactating or (post)menopausal women
- regular smokers
- people with intensive fitness training eg athletes
- habitual consumption of green or black tea (more than 1 or 2 cups a day, respectively)
- not more than 300 mg/day caffeine consumption
Trial design
Primary purpose
Allocation
Interventional model
Masking
24 participants in 2 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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