Group Interpersonal Psychotherapy for Depressed Adolescents in School-based Clinics

New York State Psychiatric Institute

Status and phase: Completed; Phase 2

Conditions: Depression

Treatments: Behavioral: Treatment as usual (TAU); Behavioral: Group interpersonal psychotherapy for depressed adolescents (IPT-AG)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00270244

DSIR 84-CTS

R01 MH73640, #5037

R01MH073640 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will assess the effectiveness of group interpersonal psychotherapy (IPT-AG) versus treatment as usual (TAU) in improving the treatment of depressed adolescents in school-based health clinics.

Full description

Depression is a serious medical condition. It occurs in people of all ages, but only in the past two decades has depression in children and adolescents been taken seriously. Children and adolescents with depression may exhibit such behaviors as pretending to be sick, refusing to go to school or getting in trouble at school, clinging to a parent or worrying that the parent may die, sulking, or acting in a negative or grouchy manner. A previous study demonstrated that, when administered by clinicians in school-based clinics, individual interpersonal psychotherapy is effective in reducing depressive symptoms and improving global and social functioning. This study will assess the effectiveness of group interpersonal psychotherapy (IPT-AG) versus treatment as usual (TAU) in improving depressive symptoms of adolescents in school-based health clinics.

Participants in this 16-week single-blind study will be randomly assigned to receive either IPT-AG or TAU in a school-based clinic. Participants assigned to receive IPT-AG will attend two to three, 40-minute individual pre-group sessions, followed by 12, 90-minute group therapy sessions and two additional individual sessions-one midway through the group sessions and another upon completion of group therapy. TAU will consist of counseling sessions as regularly conducted by the school clinic social worker and/or referral to another agency. Study visits will occur at baseline and Weeks 4, 8, 12, and 16, or upon early termination. At the end of 16 weeks, participants assigned to receive IPT-AG will continue in a maintenance program in which they will receive IPT-AG once a month for an additional 6 months. All participants will also be assessed 6 and 12 months post-treatment to measure depressive symptoms, global and social functioning, satisfaction with care, and utilization of other services.

Enrollment: 16 patients

Sex: Female

Ages: 12 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meets diagnostic criteria for major depression, dysthymic disorder, depressive disorder not otherwise specified, or adjustment disorder with depressed mood
• Score of 24 or greater on the CES-D
• Score between 10 and 28 on the HRSD
• Score of 65 or less on the C-GAS
• English-speaking
• Parental or legal guardian consent to participate

Exclusion criteria

• Actively suicidal
• Score greater than 28 on the HRSD
• Mentally retarded
• Any life threatening medical illness
• Meets diagnostic criteria for current substance abuse, schizophrenia, or bipolar disorder
• Any evidence of psychosis, conduct disorder, or active eating disorder
• Currently in active treatment for depression
• Taking antidepressant medication at the time of baseline assessment
• Recent death of someone close

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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16 participants in 2 patient groups

1

Active Comparator group

Description:

Participants will receive treatment as usual

Treatment:

Behavioral: Treatment as usual (TAU)

2

Experimental group

Description:

Participants will receive group interpersonal psychotherapy for depressed adolescents

Treatment:

Behavioral: Group interpersonal psychotherapy for depressed adolescents (IPT-AG)