Growth Hormone and Heart Failure

Assistance Publique - Hôpitaux de Paris

Status

Terminated

Conditions

Heart Failure, Congestive

Study type

Observational

Funder types

Other

Identifiers

NCT00190359

CRC00007

Details and patient eligibility

About

Heart failure induces modification in several neurohormonal systems. The aim of this study is to determine if the growth hormone/IGF1 axis is modified in heart failure patients compared to healthy volunteers.

Full description

One hundred and sixty three heart failure patients were evaluated by clinical examination, echocardiography, exercise test and measurement of blood BNP. Growth hormone and IGF-1 plasma levels were determined in each patient. The same biological measurements were performed in a group of 148 healthy controls. Comparisons were performed between groups for Growth hormone plasma level, IGF-1 plasma level and Growth hormone/IGF-1 index. A correlation between the severity of heart failure and the different biological parameters was searched.

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria