GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)

Gyroscope Therapeutics

Status: Terminated

Conditions: Macular Degeneration; Geographic Atrophy; Macular Atrophy; Retinal Degeneration; Dry Age-related Macular Degeneration; Retinal Disease

Study type: Observational

Funder types: Industry

Identifiers

NCT03894020

CPPY988A12001 (Other Identifier)

GTSCOPE

Details and patient eligibility

About

An observational study to evaluate the natural progression of dry AMD in genetically defined subjects

Full description

Prospective, observational study to evaluate the natural progression of anatomical and functional visual parameters in genetically defined subjects with GA due to AMD.

Enrollment: 83 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adults with unilateral or bilateral Geographic Atrophy (GA) due to Age-related Macular Degeneration (AMD)
2. BCVA of 40 letters or better using ETDRS charts

Exclusion criteria

1. Evidence or history of neovascular Age-related Macular Degeneration (AMD) or diabetic retinopathy
2. Significant ocular or non-ocular disease that would impact the subject's ability to participate in the study
3. Participation in another research study involving an investigational product within the previous 4 weeks or 5 half-lives whichever is longer from the screening/baseline OR received a gene/cell therapy at any time previously