Guided Bone Regeneration Versus Bone Block Grafting

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Completed

Conditions: Atrophy; Bone

Treatments: Procedure: Guided bone regeneration; Procedure: Khoury technique

Study type: Interventional

Funder types: Other

Identifiers

NCT05593198

4729

Details and patient eligibility

About

The purpose of this study is to analyze the volumetric gain and stability of the newly formed bone tissue comparing guided bone regeneration with block graft.

Enrollment: 44 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients in need of an implant-supported rehabilitation
• Patients requiring bone regeneration
• Healthy patients
• Full-mouth plaque score (FMPS) and full-mouth bleeding score (FMBS) ≤ 15%
• Sufficient mesiodistal and interocclusal space
• At least 6 months of follow-up

Exclusion criteria

• An American Society of Anesthesiologists physical status classification ≥ III
• General contraindications for surgical treatment or implant placement
• Untreated periodontitis
• Smoking
• Excessive alcohol consumption
• Any drug or medication known to affect oral status and bone turnover or contraindicate surgical treatment
• No residual keratinized tissue at the experimental area
• Unwillingness to return for follow-up examinations

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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44 participants in 2 patient groups

Guided bone regeneration

Active Comparator group

Description:

Patients will be treated with guided bone regeneration.

Treatment:

Procedure: Guided bone regeneration

Bone block

Experimental group

Description:

Patients will be treated with bone blocks using the Khoury technique.

Treatment:

Procedure: Khoury technique