Guided Tissue Regeneration With a Periodontal Dressing

Arab American University (Palestine)

Status: Completed

Conditions: Periodontal Diseases

Treatments: Procedure: Guided Tissue Regeneration; Procedure: periodontal dressing (coe-pak)

Study type: Interventional

Funder types: Other

Identifiers

NCT05756946

GTR

Details and patient eligibility

About

This randomized, controlled split-mouth study will include 24-40 patients. After GTR, a test and a control side will be selected by means of a computer-generated randomization list. Test sides will receive a periodontal dressing (Coepak") for 14 days and the control sides will receive no periodontal dressing. After 14 days the periodontal dressing will be removed and the pain experience will be recorded. After 6-9 months, the clinical periodontal parameters will be recorded.

Enrollment: 24 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 18 and 75 years.

  • A minimum of 18 teeth, wisdom teeth excluded.
  • Previously untreated moderate chronic periodontitis (Armitage 1999) with radiographic evidence of generalized alveolar bone loss >30%.
  • Presence of at least one pocket with probing pocket depth (PPD) ≥6 mm per quadrant, which was BOP.
  • Presence of at least three teeth per quadrant.

Exclusion criteria

• Periodontal treatment in the last 3 years.

  • Antibiotic intake 6 months before • the screening visit.
  • Pregnancy. Systemic diseases with an impact on periodontal healing (e.g. Dia- betes).

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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24 participants in 2 patient groups

Test group

Experimental group

Description:

Test group will receive GTR + periodontal dressing (Coe-pak)

Treatment:

Procedure: Guided Tissue Regeneration

Procedure: periodontal dressing (coe-pak)

Control group

Active Comparator group

Description:

Control group will receive GTR only

Treatment:

Procedure: Guided Tissue Regeneration