Guidelines for Post-exercise Dietary Intake in T1DM

Northumbria University

Status: Completed

Conditions: Type 1 Diabetes Mellitus

Treatments: Dietary Supplement: Meal composition

Study type: Interventional

Funder types: Other

Identifiers

NCT01794650

West-Walker2

Details and patient eligibility

About

The investigators hypothesise that manipulating the glycaemic index of the meal after exercise and before sleep will help prevent Type 1 diabetes individuals experiencing hypoglycaemia.

Enrollment: 10 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged between 18-50 years old (male or female).
• Free from any diabetes related complications (apart from mild background diabetic retinopathy).
• HbA1c <8.5%.
• Not taking any prescribed medication other than insulin, and treated with a stable insulin regimen composed of a combination of slow/long acting insulin (glargine or detemir) and fast-acting insulin analogues (lispro or aspart), for a minimum of 6 months before the start of the study.
• Demonstrate normal cardiac function in response to exercise.

Exclusion criteria

• Aged younger than 18, or older than 50 years.
• Suffering from, or diagnosed with a diabetes related complication (apart from mild background diabetic retinopathy).
• HbA1c >8.5%.
• Currently taking prescribed medication, and not currently treated with a stable basal bolus regimen composed of a combination glargine or determir, and lispro or aspart for at least 6 months before the start of the study.
• Failure to demonstrate normal cardiopulmonary responses during exercise, or have a medical condition which could prevent completion of exercise or be exacerbated because of.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

10 participants in 1 patient group

Meal composition

Other group

Description:

Changing the glycaemic index of the meals consumed after exercise and before sleep. (High GI - High GI, Low GI - Low GI, High GI - Low GI, Low GI - High GI).

Treatment:

Dietary Supplement: Meal composition