Gut Hormone Response, Appetite and Intestinal Transit Time in Good and Poor Weight Responders After Gastric Bypass (RnonR)

Hvidovre University Hospital

Status: Completed

Conditions: Obesity

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00908973

RnonR

Details and patient eligibility

About

The aim of the study is to describe differences in meal-stimulated gut hormone response, appetite and intestinal transit time between good and poor responders 1-2 years after Gastric Bypass surgery for obesity.

Enrollment: 46 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 20-60 years
• Completed laparoscopic gastric bypass surgery without complications (cases)
• No previous gastric bypass surgery (controls)

Exclusion criteria

• Diabetes
• Disease or treatment interfering with appetite or gastrointestinal motility
• Pregnancy or breastfeeding
• Excess weight loss 1 year after gastric bypass > 50% and =< 60% (cases)

Trial design

46 participants in 3 patient groups

Good responders

Description:

Excess weight loss of \> 60% 1 year after gastric bypass surgery

Poor responders

Description:

Excess weight loss of =\< 50% 1 year after gastric bypass surgery

Lean controls

Description:

Non-gastric bypass operated lean individuals, matched for age and sex