Gut Hormones After Meal Ingestion in Males Versus Females

Lund University

Status: Completed

Conditions: Normal Non-fluency

Treatments: Other: Meal ingestion

Study type: Interventional

Funder types: Other

Identifiers

NCT01366781

004

Details and patient eligibility

About

The study hypothesis is that the release of gut hormones is increased proportionally to caloric load in each meal. Three different meals with different meal size will therefore be served and gut hormones determined.

Full description

In healthy males and females, meals with 511, 743 and 1034 kcal will be given orally. Samples will be taken during the following 300 min and gut hormones (glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1) will be determined along with insulin and glucagon levels.

Enrollment: 24 patients

Sex: All

Ages: 20 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy status

Exclusion criteria

• Diabetes
• Liver disease
• kidney disease
• thyroid disease

Trial design

24 participants in 2 patient groups

Healthy males

Experimental group

Description:

Meal ingestion in healthy males

Treatment:

Other: Meal ingestion

Healthy females

Experimental group

Description:

Meal ingestion in healthy females

Treatment:

Other: Meal ingestion