Gut Microbiota Dysbiosis and Translocation During IBD and Parkinson (Medibiote1)

Hôpital Européen Marseille

Status

Completed

Conditions

Parkinson Disease

Inflammatory Bowel Diseases

Treatments

Other: stool and blood analysis

Study type

Interventional

Funder types

Other

Identifiers

NCT04159727

18-22

Details and patient eligibility

About

Inflammatory bowel diseases (IBD) and Parkinson disease (PD) are complex and multifactorial pathologies. Gut microbiota seems to play an active role. Indeed the digestive microbiota of patients with IBD or PD exhibits different compositions compared with asymptomatic subjects.

Bacterial translocation from gut to blood has been reported.

Full description

The investigators designed a case-control study to investigate the digestive microbiota and bacterial translocation during IBD and PD. The investigators want to evaluate gut microbiota bacteria involved in dysbiosis and bacterial translocation during IBD and PD. The investigators want to identify bacterial populations that can serve as biomarkers for clinical practice.

Enrollment

15 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

PD patients : age < or = 60 years
asymptomatic subjects : no chronic disease
asymptomatic subjects : no treatment

Exclusion criteria

severe anemia (Hb<7g/L)
people who don't read french
pregnant women
people treated by antibiotic, probiotic or prebiotic during the 2 month before inclusion
people with any diagnosed or treated pathology