H. Pylori Infection and AIP Levels (HP-AIP)

Tanta University

Status: Completed

Conditions: H Pylori Infection; Atherogenic Plasma Index

Treatments: Diagnostic Test: urea breath test

Study type: Observational

Funder types: Other

Identifiers

NCT07306377

Helicobacter Pylori and AIP

Details and patient eligibility

About

Helicobacter pylori is a common bacterial infection of the stomach that can cause ulcers and other digestive problems. Recent studies suggest that this infection may also affect metabolism and blood fats (lipids), which are important for heart health. Changes in lipid levels, such as higher triglycerides and lower "good" cholesterol (HDL), can increase the risk of cardiovascular disease.

This study will examine whether H. pylori infection is linked to changes in lipid profiles, especially the Atherogenic Index of Plasma (AIP). AIP is a calculation based on triglycerides and HDL cholesterol that helps predict the risk of heart disease.

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patients older than 18 years.
• Able to sign the written consent.
• Willing to participate in the research and undergo H. pylori testing. Exclusion criteria
• Unwilling to participate in the study.
• History of severe metabolic disorders.
• Taking medications that affect adipose tissue metabolism.
• History of gastric surgery.

Trial design

300 participants in 2 patient groups

Group 1A: H. pylori Positive - Normal AIP Group 1B: H. pylori Positive - Elevated AIP Group 2: H.

Treatment:

Diagnostic Test: urea breath test

Group 1A: H. pylori Positive - Normal AIP, 1B: H. pylori Positive - Elevated AIP, Group 2: H.

Treatment:

Diagnostic Test: urea breath test